637 4060 ADDRESS: 60 Mount Street Lower, Grand Canal Dock, Dublin 2 info@merrionfetalhealth.ie

Harmony Prenatal Test Dublin

Dear patients, to ensure necessary improvements so our service can continue and our clinic remains relevant in providing the highest quality ultrasound, we are making changes to our price plan from 9th January 2023. Updated prices can be found on our website. Alternatively, you can contact us on 01-6635060 or info@merrionfetalhealth.ie regarding 2023 ultrasound prices.

Harmony Test Dublin

From 10 weeks

It Is Non-Invasive?

Yes, the Harmony Test is NIPT – non-invasive prenatal testing. It analyses cell-free DNA circulating in the pregnant mother’s blood. 


Cost: €480

What Does It Test For?

It is the newest option in prenatal screening for Down syndrome (Trisomy 21) and other fetal chromosomal conditions (Trisomies 18 and 13), X and Y chromosome conditions.


    When Can It Be Used?

    This test can be requested for any singleton pregnancy, including in-vitro fertilisation (IVF) pregnancies with egg donors. It can also be requested for twin pregnancies conceived naturally or by IVF.



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    harmony prenatal test dublin

    about the

    Ariosa Harmony™

    Prenatal Test 

    DNA from the fetus circulates in the mother’s blood. Cell free DNA (cfDNA) results from the natural breakdown of fetal cells (presumed to be mostly placental) and clears from the maternal system within hours of giving birth.

    During a pregnancy, cfDNA can be tested to give the most accurate screening approach in estimating the risk of fetus having a common chromosome condition sometimes called a trisomy. This occurs when there are three copies of a particular chromosome instead of the expected two.

    The test looks to detect the following trisomies: Trisomy 21 (Down Syndrome), Trisomy 18 (Edwards syndrome) and Trisomy 13 (Patau syndrome) and Sex Chromosome Conditions.

    Refund Policy:

    If the laboratory fails to obtain a result from the initial test, you will be asked to return for a redraw. Should this happen three times, you will then be offered a refund. Please note refunds for the Harmony Non-Invasive prenatal test will be minus a scan fee of €100

    All of these are explained in our FAQs section


    Harmony Prenatal Test FAQs

    What risks are associated with the Harmony Prenatal Test?

    The testing is non-invasive: it involves taking a blood sample from the mother. The pregnancy is not put at risk of miscarriage, or from other adverse outcomes that are associated with invasive testing procedures such as amniocentesis.

    How accurate is the Harmony Prenatal Test?

    Clinical studies have shown that the Ariosa Harmony™ Prenatal Test has exceptional accuracy for assessing fetal trisomy risk.

    A “high risk” result is indicative of high risk for a trisomy. The test identifies in singleton pregnancies more than 99% of fetuses with trisomy 21, 98% of fetuses with trisomy 18, and 80% of fetuses with Turner Syndrome. X and Y analysis provide >99% accuracy for fetal sex. Accuracy detecting other sex chromosome anomalies varies by condition

    After the test, the number of women required to have a CVs or amniocentesis is less than 1%.

    It is important to note that if the test results show there is a high risk that the fetus has trisomy 21, 18, 13 or sex chromosome conditions, it does not mean that the fetus definitely has one of these conditions, although it is highly likely. For this reason, in the event of a “high risk” (or positive) result, follow-up testing by an invasive procedure is recommended.

    In the same way, if the test results show that there is a “low risk” that the fetus has trisomy 21, 18, 13 or sex chromosome conditions, it is unlikely that the fetus has one of these conditions. However, there is a very small risk that not all trisomy fetuses will be detected.

    Who can have the Harmony Test?

    Ariosa Harmony™ Prenatal Test can be ordered for women with pregnancies of at least 10 weeks’ gestational age. The Harmony™ Prenatal Test can now be ordered for all IVF Singleton pregnancies, including those with egg donors. Samples from pregnant women with twins naturally conceived, or those conceived using the patient’s own egg, are also accepted. This test does not assess risk for mosaicism, partial trisomies or translocations.

    The results will be ready in approximately two weeks. On the basis of the NIPT result and the ultrasound findings, a patient can decide whether or not she wants to have an invasive procedure such as amniocentesis or CVS.

    Why might a repeat sample be necessary for the Harmony Prenatal Test?

    There needs to be enough fetal DNA in the maternal blood sample to be able to provide a result. If there is insufficient fetal DNA in the sample (occurring in 3% of cases), another blood sample from the mother may be required. This will be processed in the laboratory at no extra charge.

    What happens at the Harmony Prenatal Test?

    Once the mother has taken an independent personal decision that she wants to have the NIPT (non-invasive prenatal test) performed, she will be asked to sign a consent form and her blood sample can be taken from a vein in her arm

    Who carries out the analysis of the Harmony test?

    The sample and completed request form are sent to TDL Genetics, after which they will be referred to Ariosa Diagnostics Inc, USA. Ariosa performs the Harmony Prenatal Test on the DNA extracted from her blood sample.

    Will the Mum-to-be need to have any other test?

    The Ariosa Harmony™ Prenatal Test does not provide information on other rare chromosomal abnormalities. If the ultrasound scan shows a high nuchal translucency or other major physical defects such as brain abnormalities, the risk for some rare chromosomal defects may be high. In such cases, the mother may choose to have a CVS or amniocentesis.

    The non-invasive prenatal test does not provide information on other physical defects such as spina bifida, or information on fetal growth. It is therefore advisable that the mother has all the usual ultrasound scans during her pregnancy.

    What is Trisomy 21?

    Trisomy 21 is the most common trisomy, at the time of birth. Also called Down syndrome, it is associated with moderate to severe intellectual disabilities and may also lead to digestive disease, congenital heart defects and other malformations.

    What are Trisomy 18 (Edwards syndrome) and Trisomy 13 (Patau syndrome)?

    Trisomy 18 (Edwards syndrome) and Trisomy 13 (Patau syndrome) are associated with a high rate of miscarriage. These babies are born with severe brain abnormalities and often have congenital heart defects as well as other birth defects. Most affected individuals die before or soon after birth, and very few survive beyond the first year of life.

    What are sex chromosome conditions?

    The sex chromosomes (X and Y) determine whether we are male or female. X and Y chromosome conditions occur when there is a missing, extra, or incomplete copy of one of the sex chromosomes. The Harmony with X, Y test can assess risk for XXX, XYY, XXYY, XXY (Klinefelter Syndrome), and a missing X chromosome in a girl (Turner Syndrome). There is significant variability in the severity of these conditions, but most individuals have mild, if any, physical or behavioural features. If the mother is interested in having this optional testing, she should talk with her healthcare provider to determine if it is right for her.


    Nuchal Translucency

    12-14 weeks


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    20-22 weeks


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    10-17 weeks


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    19 weeks onwards


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    22 weeks onwards


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    40 weeks onwards


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    What Our Patients Say

    Gráinne Macken

    This is my second visit to Merrion Fetal, I was very pleased on both occasions. Lovely quiet waiting room, appointment was on time. The 20-week scan is very detailed we enjoyed watching our baby on the large TV screen. We got some beautiful photos. The nurse was very pleasant and talked us through all the measurements and anatomy. I would highly recommend this scanning clinic.”

    Áine Gibney

    I had the best experience at the Merrion Fetal Health clinic for my 20-week big scan. The staff were so friendly and so nice and the lovely lady who did my ultrasound scan was amazing. She was so thoroughgoing to absolutely everything and gave me such reassurance on how my baby was growing and developing. I would recommend any Mother to be to attend here if you are looking for a comfortable, reassuring and super pleasant experience.”

    Linda O'Sullivan

    Highly recommend! We had an early scan due to a little scare at the start of pregnancy and then another at 12 weeks to make sure all was good again. Helen who was scanning on both days was fantastic. We felt totally relaxed and un-rushed while she took her time finding the best angle of baby to get us the clearest pictures as keepsakes all while making sure everything was perfect with baby. She reassured us throughout and I can honestly say it was the best money we ever spent getting both scans done.

    Please let Helen know we are 18 weeks now and flying along Highly recommend!



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    All articles on the blog and website are intended as information only. Please do not consider any of the information provided here as a substitute for medical advice. At all times seek medical advice directly with your own doctor and medical team.